[Thymus cancers: A clinical observation]. / Thymustumoren : Eine klinische Betrachtung.
Pathologe
; 37(1): 91-105; quiz 106, 2016 Feb.
Article
em De
| MEDLINE
| ID: mdl-26821326
ABSTRACT
INTRODUCTION:
Thymic tumors including thymomas, thymic carcinomas, and thymic carcinoid tumors are rare tumors with an incidence of 0.13/100,000. MATERIALS ANDMETHODS:
A literature search was performed to identify recent findings on epidemiology, classification, and various therapeutic approaches.RESULTS:
These tumors with a wide spectrum of histologic and biologic features may be clinically unapparent for a long time or show a very aggressive behavior with local invasion and distant metastases. Surgical resection is the mainstay in stage I and II thymomas, whereas in stage III thymomas and in thymomas with pleural dissemination surgery in context of a multimodal treatment should be discussed. Thymic tumors are chemoreactive. Targeted therapies show poor results and should only be considered in the palliative situation after failure of chemotherapy.CONCLUSION:
The new TNM (T tumor, N node, M metastasis) classification of thymic tumors will help to identify the best treatment options.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Timoma
/
Neoplasias do Timo
/
Tumor Carcinoide
/
Carcinoma
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
De
Ano de publicação:
2016
Tipo de documento:
Article