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G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.
Mesirca, Pietro; Bidaud, Isabelle; Briec, François; Evain, Stéphane; Torrente, Angelo G; Le Quang, Khai; Leoni, Anne-Laure; Baudot, Matthias; Marger, Laurine; Chung You Chong, Antony; Nargeot, Joël; Striessnig, Joerg; Wickman, Kevin; Charpentier, Flavien; Mangoni, Matteo E.
Afiliação
  • Mesirca P; Département de Physiologie, Institut de Genomique Fonctionnelle, Laboratory of Excellence in Ion Channel Science and Therapeutics, UMR-5203, CNRS, F-34094 Montpellier, France; INSERM U661, F-34094 Montpellier, France; Université de Montpellier, F-34094 Montpellier, France; pietro.mesirca@igf.cnrs.fr
  • Bidaud I; Département de Physiologie, Institut de Genomique Fonctionnelle, Laboratory of Excellence in Ion Channel Science and Therapeutics, UMR-5203, CNRS, F-34094 Montpellier, France; INSERM U661, F-34094 Montpellier, France; Université de Montpellier, F-34094 Montpellier, France;
  • Briec F; INSERM, UMR_S1087, l'Institut du Thorax, F-44007 Nantes, France;
  • Evain S; INSERM, UMR_S1087, l'Institut du Thorax, F-44007 Nantes, France;
  • Torrente AG; Département de Physiologie, Institut de Genomique Fonctionnelle, Laboratory of Excellence in Ion Channel Science and Therapeutics, UMR-5203, CNRS, F-34094 Montpellier, France; INSERM U661, F-34094 Montpellier, France; Université de Montpellier, F-34094 Montpellier, France;
  • Le Quang K; INSERM, UMR_S1087, l'Institut du Thorax, F-44007 Nantes, France; Université de Nantes, F-44007 Nantes, France;
  • Leoni AL; INSERM U661, F-34094 Montpellier, France;
  • Baudot M; Département de Physiologie, Institut de Genomique Fonctionnelle, Laboratory of Excellence in Ion Channel Science and Therapeutics, UMR-5203, CNRS, F-34094 Montpellier, France; INSERM U661, F-34094 Montpellier, France; Université de Montpellier, F-34094 Montpellier, France;
  • Marger L; Département de Physiologie, Institut de Genomique Fonctionnelle, Laboratory of Excellence in Ion Channel Science and Therapeutics, UMR-5203, CNRS, F-34094 Montpellier, France; INSERM U661, F-34094 Montpellier, France; Université de Montpellier, F-34094 Montpellier, France;
  • Chung You Chong A; Département de Physiologie, Institut de Genomique Fonctionnelle, Laboratory of Excellence in Ion Channel Science and Therapeutics, UMR-5203, CNRS, F-34094 Montpellier, France; INSERM U661, F-34094 Montpellier, France; Université de Montpellier, F-34094 Montpellier, France;
  • Nargeot J; Département de Physiologie, Institut de Genomique Fonctionnelle, Laboratory of Excellence in Ion Channel Science and Therapeutics, UMR-5203, CNRS, F-34094 Montpellier, France; INSERM U661, F-34094 Montpellier, France; Université de Montpellier, F-34094 Montpellier, France;
  • Striessnig J; Institute of Pharmacy, Pharmacology and Toxicology and Center of Molecular Biosciences Innsbruck, A-6020 Innsbruck, Austria;
  • Wickman K; Department of Pharmacology, University of Minnesota, Minneapolis, MN 554557;
  • Charpentier F; INSERM, UMR_S1087, l'Institut du Thorax, F-44007 Nantes, France; Université de Nantes, F-44007 Nantes, France; CNRS UMR 6291, l'Institut du Thorax, F-44007 Nantes, France; Centre Hospitalier Universitaire Nantes, F-44007 Nantes, France.
  • Mangoni ME; Département de Physiologie, Institut de Genomique Fonctionnelle, Laboratory of Excellence in Ion Channel Science and Therapeutics, UMR-5203, CNRS, F-34094 Montpellier, France; INSERM U661, F-34094 Montpellier, France; Université de Montpellier, F-34094 Montpellier, France; pietro.mesirca@igf.cnrs.fr
Proc Natl Acad Sci U S A ; 113(7): E932-41, 2016 Feb 16.
Article em En | MEDLINE | ID: mdl-26831068
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome do Nó Sinusal / Ativação do Canal Iônico / Proteínas de Ligação ao GTP / Canais de Cálcio Tipo L / Bloqueio Cardíaco Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome do Nó Sinusal / Ativação do Canal Iônico / Proteínas de Ligação ao GTP / Canais de Cálcio Tipo L / Bloqueio Cardíaco Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article