Molecular Mechanisms of Nickel Allergy.
Int J Mol Sci
; 17(2)2016 Feb 02.
Article
em En
| MEDLINE
| ID: mdl-26848658
ABSTRACT
Allergic contact hypersensitivity to metals is a delayed-type allergy. Although various metals are known to produce an allergic reaction, nickel is the most frequent cause of metal allergy. Researchers have attempted to elucidate the mechanisms of metal allergy using animal models and human patients. Here, the immunological and molecular mechanisms of metal allergy are described based on the findings of previous studies, including those that were recently published. In addition, the adsorption and excretion of various metals, in particular nickel, is discussed to further understand the pathogenesis of metal allergy.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Oligoelementos
/
Alérgenos
/
Hipersensibilidade
/
Níquel
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article