Effects of alanine:glyoxylate aminotransferase variants and pyridoxine sensitivity on oxalate metabolism in a cell-based cytotoxicity assay.

Fargue, Sonia; Knight, John; Holmes, Ross P; Rumsby, Gill; Danpure, Christopher J

Fargue, Sonia; Knight, John; Holmes, Ross P; Rumsby, Gill; Danpure, Christopher J.

Afiliação

Fargue S; Department of Cell & Developmental Biology, University College London, London WC1E 6BT, UK; Department of Urology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: sfargue@uab.edu.
Knight J; Department of Urology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Holmes RP; Department of Urology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Rumsby G; Department of Clinical Biochemistry, University College London Hospitals, London W1T 4EU, UK.
Danpure CJ; Department of Cell & Developmental Biology, University College London, London WC1E 6BT, UK.

Biochim Biophys Acta ; 1862(6): 1055-62, 2016 06.

Article em En | MEDLINE | ID: mdl-26854734

Assuntos

Hiperoxalúria Primária/metabolismo; Oxalatos/metabolismo; Piridoxina/metabolismo; Transaminases/metabolismo; Animais; Células CHO; Sobrevivência Celular; Cricetulus; Glicolatos/metabolismo; Humanos; Hiperoxalúria Primária/genética; Mutação; Espécies Reativas de Oxigênio/metabolismo; Transaminases/genética

Palavras-chave

Alanine:glyoxylate aminotransferase; Glyoxylate; Kidney stones; Oxalate; Primary hyperoxaluria; Pyridoxine

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxalatos / Piridoxina / Hiperoxalúria Primária / Transaminases Tipo de estudo: Diagnostic_studies / Guideline Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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