Inhibition of Soluble Tumor Necrosis Factor Prevents Chemically Induced Carcinogenesis in Mice.

Sobo-Vujanovic, Andrea; Vujanovic, Lazar; DeLeo, Albert B; Concha-Benavente, Fernando; Ferris, Robert L; Lin, Yan; Vujanovic, Nikola L

Sobo-Vujanovic, Andrea; Vujanovic, Lazar; DeLeo, Albert B; Concha-Benavente, Fernando; Ferris, Robert L; Lin, Yan; Vujanovic, Nikola L.

Afiliação

Sobo-Vujanovic A; University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania.
Vujanovic L; University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania. Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
DeLeo AB; University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania. Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania. Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Concha-Benavente F; University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania. Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania. Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Ferris RL; University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania. Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania. Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Lin Y; University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania. Department of Biostatistics, University of Pittsburgh, Pittsburgh, Pennsylvania.
Vujanovic NL; University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania. Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania. Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania. vujanovicnl@upmc.edu.

Cancer Immunol Res ; 4(5): 441-51, 2016 05.

Article em En | MEDLINE | ID: mdl-26896171

Assuntos

Neoplasias Experimentais/prevenção & controle; Fator de Necrose Tumoral alfa/antagonistas & inibidores; Animais; Antineoplásicos/farmacologia; Antineoplásicos/uso terapêutico; Carcinogênese/efeitos dos fármacos; Citocinas/biossíntese; Células Dendríticas/imunologia; Avaliação Pré-Clínica de Medicamentos/métodos; Feminino; Deleção de Genes; Tolerância Imunológica; Células Matadoras Naturais/imunologia; Metilcolantreno; Camundongos Endogâmicos C57BL; Camundongos SCID; Terapia de Alvo Molecular/métodos; Neoplasias Experimentais/induzido quimicamente; Neoplasias Experimentais/imunologia; Neoplasias Experimentais/patologia; Receptores Tipo I de Fatores de Necrose Tumoral/genética; Fator de Transcrição STAT3/metabolismo; Solubilidade; Fator de Necrose Tumoral alfa/genética; Fator de Necrose Tumoral alfa/farmacologia; Fator de Necrose Tumoral alfa/uso terapêutico

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator de Necrose Tumoral alfa / Neoplasias Experimentais Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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