Outcomes of dialysis and the transplantation options for patients with diabetic end-stage renal disease in Korea.
Clin Transplant
; 30(5): 534-44, 2016 05.
Article
em En
| MEDLINE
| ID: mdl-26914661
ABSTRACT
BACKGROUND:
The best therapeutic option for diabetic end-stage renal disease (DMESRD) has not been established among living donor kidney transplantation (LDKT), deceased donor kidney transplantation (DDKT), simultaneous pancreas and kidney transplantation (SPK), and dialysis.METHODS:
We retrospectively analyzed the outcomes of DMESRD patients at two Korean centers from February 2000 to December 2011.RESULTS:
Among 674 patients, 295 underwent kidney transplantation (LDKT, 175; DDKT, 72; and SPK, 48), while 379 were still on dialysis. The dialysis group had a higher mortality rate than the transplantation group. From the time after dialysis initiation, LDKT group had a better patient survival rate than DDKT registration group and SPK registration group. From the time after transplantation, LDKT had a better patient survival rate than DDKT; however, there was no significant difference between LDKT and SPK. In SPK, patient survival and kidney or pancreas graft survival rates were not different between types 1 and 2 DMESRD.CONCLUSION:
LDKT is better than waiting for SPK/DDKT in DMESRD patients, if a living donor is available, and this conclusion may be unique to Korea where waiting time for SPK is long. SPK can be used in non-obese Asians with type 2 as well as type 1 DMESRD.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Diálise Renal
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Transplante de Rim
/
Transplante de Pâncreas
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Diabetes Mellitus Tipo 1
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Diabetes Mellitus Tipo 2
/
Rejeição de Enxerto
/
Falência Renal Crônica
Tipo de estudo:
Etiology_studies
/
Observational_studies
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Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
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Male
/
Middle aged
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article