Pharmacodynamic modeling of adverse effects of anti-cancer drug treatment.

de Vries Schultink, A H M; Suleiman, A A; Schellens, J H M; Beijnen, J H; Huitema, A D R

de Vries Schultink, A H M; Suleiman, A A; Schellens, J H M; Beijnen, J H; Huitema, A D R.

Afiliação

de Vries Schultink AH; Department of Pharmacy and Pharmacology, Antoni van Leeuwenhoek-The Netherlands Cancer Institute and MC Slotervaart, Louwesweg 6, 1066 EC, Amsterdam, The Netherlands. ah.d.vriesschultink@nki.nl.
Suleiman AA; Department of Pharmacology, Clinical Pharmacology Unit, University Hospital of Cologne, Gleueler Str. 24, 50931, Cologne, Germany.
Schellens JH; Department of Clinical Pharmacology, Antoni van Leeuwenhoek-The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.
Beijnen JH; Science Faculty, Utrecht Institute for Pharmaceutical Sciences (UIPS), Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, P.O. Box 80082, 3508 TB, Utrecht, The Netherlands.
Huitema AD; Department of Pharmacy and Pharmacology, Antoni van Leeuwenhoek-The Netherlands Cancer Institute and MC Slotervaart, Louwesweg 6, 1066 EC, Amsterdam, The Netherlands.

Eur J Clin Pharmacol ; 72(6): 645-53, 2016 Jun.

Article em En | MEDLINE | ID: mdl-26915815

Assuntos

Antineoplásicos/efeitos adversos; Modelos Biológicos; Relação Dose-Resposta a Droga; Humanos

Palavras-chave

Adverse effects; Anti-cancer drug treatment; Modeling; Pharmacodynamics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Modelos Biológicos / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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