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Computing the Internode Certainty and Related Measures from Partial Gene Trees.
Kobert, Kassian; Salichos, Leonidas; Rokas, Antonis; Stamatakis, Alexandros.
Afiliação
  • Kobert K; Heidelberg Institute for Theoretical Studies, Heidelberg, Germany Kassian.Kobert@gmail.com.
  • Salichos L; Department of Molecular Biophysics and Biochemistry, Yale University Department of Biological Sciences, Vanderbilt University.
  • Rokas A; Department of Biological Sciences, Vanderbilt University Department of Biomedical Informatics, Vanderbilt University Medical Center.
  • Stamatakis A; Heidelberg Institute for Theoretical Studies, Heidelberg, Germany Institute for Theoretical Informatics, Karlsruhe Institute of Technology, Postfach 6980, Karlsruhe, 76128, Germany.
Mol Biol Evol ; 33(6): 1606-17, 2016 06.
Article em En | MEDLINE | ID: mdl-26915959
ABSTRACT
We present, implement, and evaluate an approach to calculate the internode certainty (IC) and tree certainty (TC) on a given reference tree from a collection of partial gene trees. Previously, the calculation of these values was only possible from a collection of gene trees with exactly the same taxon set as the reference tree. An application to sets of partial gene trees requires mathematical corrections in the IC and TC calculations. We implement our methods in RAxML and test them on empirical datasets. These tests imply that the inclusion of partial trees does matter. However, in order to provide meaningful measurements, any dataset should also include trees containing the full species set.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biologia Computacional / Modelos Genéticos Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biologia Computacional / Modelos Genéticos Idioma: En Ano de publicação: 2016 Tipo de documento: Article