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HCV induces transforming growth factor ß1 through activation of endoplasmic reticulum stress and the unfolded protein response.
Chusri, Pattranuch; Kumthip, Kattareeya; Hong, Jian; Zhu, Chuanlong; Duan, Xiaoqiong; Jilg, Nikolaus; Fusco, Dahlene N; Brisac, Cynthia; Schaefer, Esperance A; Cai, Dachuan; Peng, Lee F; Maneekarn, Niwat; Lin, Wenyu; Chung, Raymond T.
Afiliação
  • Chusri P; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
  • Kumthip K; Department of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
  • Hong J; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
  • Zhu C; Department of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
  • Duan X; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
  • Jilg N; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
  • Fusco DN; Department of Infectious Diseases, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
  • Brisac C; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
  • Schaefer EA; Institute of Blood Transfusion, Chinese Academy of Medical Sciences and Peking Union Medical College, Chengdu, China.
  • Cai D; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
  • Peng LF; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
  • Maneekarn N; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
  • Lin W; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
  • Chung RT; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Sci Rep ; 6: 22487, 2016 Mar 01.
Article em En | MEDLINE | ID: mdl-26927933
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: NF-kappa B / Proteínas Serina-Treonina Quinases / Hepacivirus / Proteínas Quinases JNK Ativadas por Mitógeno / Endorribonucleases / Fator de Crescimento Transformador beta1 / Resposta a Proteínas não Dobradas / Estresse do Retículo Endoplasmático Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: NF-kappa B / Proteínas Serina-Treonina Quinases / Hepacivirus / Proteínas Quinases JNK Ativadas por Mitógeno / Endorribonucleases / Fator de Crescimento Transformador beta1 / Resposta a Proteínas não Dobradas / Estresse do Retículo Endoplasmático Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article