Development of Solid-Phase Site-Specific Conjugation and Its Application toward Generation of Dual Labeled Antibody and Fab Drug Conjugates.

Puthenveetil, Sujiet; Musto, Sylvia; Loganzo, Frank; Tumey, L Nathan; O'Donnell, Christopher J; Graziani, Edmund

Puthenveetil, Sujiet; Musto, Sylvia; Loganzo, Frank; Tumey, L Nathan; O'Donnell, Christopher J; Graziani, Edmund.

Afiliação

Puthenveetil S; Worldwide Medicinal Chemistry, Pfizer Global R&D , Groton, Connecticut 06340, United States.
Musto S; Pfizer Oncology-Rinat R&D , 401 North Middletown Road, Pearl River, New York 10965, United States.
Loganzo F; Pfizer Oncology-Rinat R&D , 401 North Middletown Road, Pearl River, New York 10965, United States.
Tumey LN; Worldwide Medicinal Chemistry, Pfizer Global R&D , Groton, Connecticut 06340, United States.
O'Donnell CJ; Worldwide Medicinal Chemistry, Pfizer Global R&D , Groton, Connecticut 06340, United States.
Graziani E; Worldwide Medicinal Chemistry, Pfizer Global R&D , Groton, Connecticut 06340, United States.

Bioconjug Chem ; 27(4): 1030-9, 2016 Apr 20.

Article em En | MEDLINE | ID: mdl-26942771

Assuntos

Anticorpos/química; Imunoconjugados/química; Fragmentos Fab das Imunoglobulinas/química

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos Fab das Imunoglobulinas / Imunoconjugados / Anticorpos Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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