&#945;-Smooth muscle actin is an inconsistent marker of fibroblasts responsible for force-dependent TGFß activation or collagen production across multiple models of organ fibrosis.

Sun, Kai-Hui; Chang, Yongen; Reed, Nilgun I; Sheppard, Dean

α-Smooth muscle actin is an inconsistent marker of fibroblasts responsible for force-dependent TGFß activation or collagen production across multiple models of organ fibrosis.

Sun, Kai-Hui; Chang, Yongen; Reed, Nilgun I; Sheppard, Dean.

Afiliação

Sun KH; Lung Biology Center, Department of Medicine, University of California, San Francisco; and.
Chang Y; Lung Biology Center, Department of Medicine, University of California, San Francisco; and Division of Nephrology, Department of Medicine, University of California, Irvine, Orange, California.
Reed NI; Lung Biology Center, Department of Medicine, University of California, San Francisco; and.
Sheppard D; Lung Biology Center, Department of Medicine, University of California, San Francisco; and dean.sheppard@ucsf.edu.

Am J Physiol Lung Cell Mol Physiol ; 310(9): L824-36, 2016 05 01.

Article em En | MEDLINE | ID: mdl-26944089

Assuntos

Actinas/metabolismo; Colágeno/biossíntese; Fibroblastos/metabolismo; Fator de Crescimento Transformador beta/fisiologia; Animais; Biomarcadores/metabolismo; Células Cultivadas; Integrinas/metabolismo; Rim/metabolismo; Rim/patologia; Pulmão/metabolismo; Pulmão/patologia; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Fibrose Pulmonar/metabolismo; Fibrose Pulmonar/patologia; Receptores do Fator de Crescimento Derivado de Plaquetas/metabolismo

Palavras-chave

fibrosis; integrin; αSMA

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator de Crescimento Transformador beta / Actinas / Colágeno / Fibroblastos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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