Your browser doesn't support javascript.
loading
Dichotomous Relationship Between Age and 30-Day Death or Rehospitalization in Heart Failure Patients Admitted With Acute Decompensated Heart Failure: Results From the ASCEND-HF Trial.
Whellan, David J; Stebbins, Amanda; Hernandez, Adrian F; Ezekowitz, Justin A; McMurray, John J V; Mather, Paul J; Hasselblad, Vic; O'Connor, Christopher M.
Afiliação
  • Whellan DJ; Thomas Jefferson University, Sidney Kimmel Medical College, Philadelphia, Pennsylvania, USA. Electronic address: david.whellan@jefferson.edu.
  • Stebbins A; Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA.
  • Hernandez AF; Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA.
  • Ezekowitz JA; Canadian VIGOUR Centre at the University of Alberta, Mazankowski Alberta Heart Institute, Li Ka Shing Centre for Health Research Innovation, University of Alberta, Edmonton, Alberta, Canada.
  • McMurray JJ; Western Infirmary and the British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland, United Kingdom.
  • Mather PJ; Thomas Jefferson University, Sidney Kimmel Medical College, Philadelphia, Pennsylvania, USA.
  • Hasselblad V; Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA.
  • O'Connor CM; Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA.
J Card Fail ; 22(6): 409-16, 2016 Jun.
Article em En | MEDLINE | ID: mdl-26952241
BACKGROUND: Younger age as an independent predictor of death or all-cause rehospitalization at 30 days post-randomization for hospitalized heart failure (HF) patients has not been well described. METHODS AND RESULTS: ASCEND-HF enrolled 7141 hospitalized acute HF patients (categorized by age: <45, 45 to <55, 55 to <65, 65 to <75, and ≥75 years) and followed them for 30 days to assess clinical outcomes, which included death or rehospitalization. Patients 45 to <55 years had the lowest percentages of death (1.4%) and total rehospitalizations (10.7%); percentages increased for younger (3.0% and 12.2%, respectively, for age <45 y) and older (5.8% and 12.5%, respectively, for age ≥75 y) patients. For those rehospitalized, the total HF-induced readmissions were highest in the youngest (68%) and declined with increasing age (P = .03). Although patients ≥55 years of age were more likely to die or be rehospitalized within 30 days of randomization for each additional 10 years of life, those <55 years of age had a significant reduction in death or HF rehospitalization for each 10-year increase in age (similar findings for death and HF rehospitalization). CONCLUSIONS: There is a dichotomous relationship between age and risk of death or rehospitalization, and death or HF rehospitalization-risk decreases as age increases up to age 55 years, then increases after age 55 years.
Assuntos
Palavras-chave

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Readmissão do Paciente / Medição de Risco / Insuficiência Cardíaca Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged País como assunto: America do norte Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Readmissão do Paciente / Medição de Risco / Insuficiência Cardíaca Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged País como assunto: America do norte Idioma: En Ano de publicação: 2016 Tipo de documento: Article