Deposition, structure, physical and invitro characteristics of Ag-doped ß-Ca3(PO4)2/chitosan hybrid composite coatings on Titanium metal.
Mater Sci Eng C Mater Biol Appl
; 62: 692-701, 2016 May.
Article
em En
| MEDLINE
| ID: mdl-26952474
ABSTRACT
Pure and five silver-doped (0-5Ag) ß-tricalcium phosphate [ß-TCP, ß-Ca3(PO4)2]/chitosan composite coatings were deposited on Titanium (Ti) substrates and their properties that are relevant for applications in hard tissue replacements were assessed. Silver, ß-TCP and chitosan were combined to profit from their salient and complementary antibacterial and biocompatible features.The ß-Ca3(PO4)2 powders were synthesized by co-precipitation. The characterization results confirmed the Ag(+) occupancy at the crystal lattice of ß-Ca3(PO4)2. The Ag-dopedß-Ca3(PO4)2/chitosan composite coatings deposited by electrophoresis showed good antibacterial activity and exhibited negative cytotoxic effects towards the human osteosarcoma cell line MG-63. The morphology of the coatings was observed by SEM and their efficiency against corrosion of metallic substrates was determined through potentiodynamic polarization tests.
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Base de dados:
MEDLINE
Assunto principal:
Prata
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Titânio
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Fosfatos de Cálcio
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Materiais Revestidos Biocompatíveis
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Quitosana
Limite:
Humans
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article