[How to define treatment-resistant depression?]. / Quelle définition pour la dépression résistante ?
Presse Med
; 45(3): 323-8, 2016 Mar.
Article
em Fr
| MEDLINE
| ID: mdl-26970938
ABSTRACT
The most largely used definition of the treatment-resistant depression relies on the failure of two successive trials of antidepressant treatment at an adequate dose and duration. The absence of response to previous antidepressant treatments should be assessed using specific and appropriate clinical instruments enabling a correct staging of the therapeutic resistance. A wide range of socio-demographic and clinical factors (i.e. psychiatric/somatic comorbidities) are classically associated with the therapeutic resistance. The aim of the treatment of major depression is to achieve a complete clinical remission. The presence of residual symptoms increases the risk for the subsequent occurrence of relapses and recurrences, hence facilitating the development of therapeutic resistance. The treatment-resistant depression has a deleterious impact on the social, familial or professional functioning, thereby leading to an impaired quality of life with serious socioeconomic consequences and costs.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Transtorno Depressivo
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
Fr
Ano de publicação:
2016
Tipo de documento:
Article