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Human PCSK9 promotes hepatic lipogenesis and atherosclerosis development via apoE- and LDLR-mediated mechanisms.
Tavori, Hagai; Giunzioni, Ilaria; Predazzi, Irene M; Plubell, Deanna; Shivinsky, Anna; Miles, Joshua; Devay, Rachel M; Liang, Hong; Rashid, Shirya; Linton, MacRae F; Fazio, Sergio.
Afiliação
  • Tavori H; Knight Cardiovascular Institute, Center for Preventive Cardiology, Oregon Health and Science University, Portland, OR, USA fazio@ohsu.edu tavori@ohsu.edu.
  • Giunzioni I; Knight Cardiovascular Institute, Center for Preventive Cardiology, Oregon Health and Science University, Portland, OR, USA.
  • Predazzi IM; Knight Cardiovascular Institute, Center for Preventive Cardiology, Oregon Health and Science University, Portland, OR, USA.
  • Plubell D; Knight Cardiovascular Institute, Center for Preventive Cardiology, Oregon Health and Science University, Portland, OR, USA.
  • Shivinsky A; Knight Cardiovascular Institute, Center for Preventive Cardiology, Oregon Health and Science University, Portland, OR, USA.
  • Miles J; Knight Cardiovascular Institute, Center for Preventive Cardiology, Oregon Health and Science University, Portland, OR, USA.
  • Devay RM; Rinat Laboratory, Pfizer Inc., South San Francisco, CA, USA.
  • Liang H; Rinat Laboratory, Pfizer Inc., South San Francisco, CA, USA.
  • Rashid S; Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada Dalhousie Medicine New Brunswick University, Saint John, New Brunswick, Canada.
  • Linton MF; Division of Cardiovascular Medicine, Atherosclerosis Research Unit, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Fazio S; Knight Cardiovascular Institute, Center for Preventive Cardiology, Oregon Health and Science University, Portland, OR, USA fazio@ohsu.edu tavori@ohsu.edu.
Cardiovasc Res ; 110(2): 268-78, 2016 May 15.
Article em En | MEDLINE | ID: mdl-26980204

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepatócitos / Aterosclerose / Lipogênese / Pró-Proteína Convertase 9 Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepatócitos / Aterosclerose / Lipogênese / Pró-Proteína Convertase 9 Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article