Statin Concentrations Below the Minimum Inhibitory Concentration Attenuate the Virulence of Rhizopus oryzae.

Bellanger, Anne-Pauline; Tatara, Alexander M; Shirazi, Fazal; Gebremariam, Teclegiorgis; Albert, Nathaniel D; Lewis, Russell E; Ibrahim, Ashraf S; Kontoyiannis, Dimitrios P

Bellanger, Anne-Pauline; Tatara, Alexander M; Shirazi, Fazal; Gebremariam, Teclegiorgis; Albert, Nathaniel D; Lewis, Russell E; Ibrahim, Ashraf S; Kontoyiannis, Dimitrios P.

Afiliação

Bellanger AP; Department of Infectious Disease, Infection Control, and Employee Health, University of Texas MD Anderson Cancer Center, Houston.
Tatara AM; Department of Infectious Disease, Infection Control, and Employee Health, University of Texas MD Anderson Cancer Center, Houston.
Shirazi F; Department of Infectious Disease, Infection Control, and Employee Health, University of Texas MD Anderson Cancer Center, Houston.
Gebremariam T; Division of Infectious Disease, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center.
Albert ND; Department of Infectious Disease, Infection Control, and Employee Health, University of Texas MD Anderson Cancer Center, Houston.
Lewis RE; Department of Medical Science and Surgery, University Orsola-Malpighi, Bologna, Italy.
Ibrahim AS; Division of Infectious Disease, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center.
Kontoyiannis DP; Department of Infectious Disease, Infection Control, and Employee Health, University of Texas MD Anderson Cancer Center, Houston.

J Infect Dis ; 214(1): 114-21, 2016 07 01.

Article em En | MEDLINE | ID: mdl-26984141

Assuntos

Antifúngicos/farmacologia; Antifúngicos/uso terapêutico; Inibidores de Hidroximetilglutaril-CoA Redutases/uso terapêutico; Mucormicose/tratamento farmacológico; Rhizopus/efeitos dos fármacos; Virulência/efeitos dos fármacos; Animais; Atorvastatina/farmacologia; Atorvastatina/uso terapêutico; Dípteros/efeitos dos fármacos; Chaperona BiP do Retículo Endoplasmático; Feminino; Humanos; Lovastatina/farmacologia; Lovastatina/uso terapêutico; Camundongos; Testes de Sensibilidade Microbiana; Sinvastatina/farmacologia; Sinvastatina/uso terapêutico; Esporos Fúngicos/efeitos dos fármacos; Texas

Palavras-chave

Rhizopus oryzae; apoptosis; fly model; germination; murine model; statins; virulence

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rhizopus / Virulência / Inibidores de Hidroximetilglutaril-CoA Redutases / Mucormicose / Antifúngicos Limite: Animals / Female / Humans País como assunto: America do norte Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google