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HSP70 Inhibition Limits FAK-Dependent Invasion and Enhances the Response to Melanoma Treatment with BRAF Inhibitors.
Budina-Kolomets, Anna; Webster, Marie R; Leu, Julia I-Ju; Jennis, Matthew; Krepler, Clemens; Guerrini, Anastasia; Kossenkov, Andrew V; Xu, Wei; Karakousis, Giorgos; Schuchter, Lynn; Amaravadi, Ravi K; Wu, Hong; Yin, Xiangfan; Liu, Qin; Lu, Yiling; Mills, Gordon B; Xu, Xiaowei; George, Donna L; Weeraratna, Ashani T; Murphy, Maureen E.
Afiliação
  • Budina-Kolomets A; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Webster MR; Program in Tumor Microenvironment and Metastasis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Leu JI; Department of Genetics, The Perelman School of Medicine, the University of Pennsylvania, Philadelphia, Pennsylvania.
  • Jennis M; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Krepler C; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Guerrini A; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Kossenkov AV; Center for Systems and Computational Biology, The Wistar Institute, Philadelphia, Pennsylvania.
  • Xu W; Department of Medicine, The Perelman School of Medicine, the University of Pennsylvania, Philadelphia, Pennsylvania.
  • Karakousis G; Department of Surgery, The Perelman School of Medicine, the University of Pennsylvania, Philadelphia, Pennsylvania.
  • Schuchter L; Department of Medicine, The Perelman School of Medicine, the University of Pennsylvania, Philadelphia, Pennsylvania.
  • Amaravadi RK; Department of Medicine, The Perelman School of Medicine, the University of Pennsylvania, Philadelphia, Pennsylvania.
  • Wu H; Department of Pathology, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
  • Yin X; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Liu Q; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Lu Y; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Mills GB; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Xu X; Department of Pathology and Laboratory Medicine, and Abramson Cancer Center, The Perelman School of Medicine, the University of Pennsylvania, Philadelphia, Pennsylvania.
  • George DL; Department of Genetics, The Perelman School of Medicine, the University of Pennsylvania, Philadelphia, Pennsylvania.
  • Weeraratna AT; Program in Tumor Microenvironment and Metastasis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Murphy ME; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania. mmurphy@wistar.org.
Cancer Res ; 76(9): 2720-30, 2016 05 01.
Article em En | MEDLINE | ID: mdl-26984758
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfonamidas / Proteínas de Choque Térmico HSP70 / Quinase 1 de Adesão Focal / Indóis / Melanoma / Antineoplásicos Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfonamidas / Proteínas de Choque Térmico HSP70 / Quinase 1 de Adesão Focal / Indóis / Melanoma / Antineoplásicos Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article