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Treatment of experimental human breast cancer and lung cancer brain metastases in mice by macitentan, a dual antagonist of endothelin receptors, combined with paclitaxel.
Lee, Ho Jeong; Hanibuchi, Masaki; Kim, Sun-Jin; Yu, Hyunkyung; Kim, Mark Seungwook; He, Junqin; Langley, Robert R; Lehembre, François; Regenass, Urs; Fidler, Isaiah J.
Afiliação
  • Lee HJ; Department of Cancer Biology, Metastasis Research Laboratory, The University of Texas MD Anderson Cancer Center, Houston, Texas (H.J.L., M.H., S.-J.K., H.Y., M.S.K., J.H., R.R.L., I.J.F.); Actelion Pharmaceuticals, Ltd., Allschwil, Switzerland (F.L., U.R.).
  • Hanibuchi M; Department of Cancer Biology, Metastasis Research Laboratory, The University of Texas MD Anderson Cancer Center, Houston, Texas (H.J.L., M.H., S.-J.K., H.Y., M.S.K., J.H., R.R.L., I.J.F.); Actelion Pharmaceuticals, Ltd., Allschwil, Switzerland (F.L., U.R.).
  • Kim SJ; Department of Cancer Biology, Metastasis Research Laboratory, The University of Texas MD Anderson Cancer Center, Houston, Texas (H.J.L., M.H., S.-J.K., H.Y., M.S.K., J.H., R.R.L., I.J.F.); Actelion Pharmaceuticals, Ltd., Allschwil, Switzerland (F.L., U.R.).
  • Yu H; Department of Cancer Biology, Metastasis Research Laboratory, The University of Texas MD Anderson Cancer Center, Houston, Texas (H.J.L., M.H., S.-J.K., H.Y., M.S.K., J.H., R.R.L., I.J.F.); Actelion Pharmaceuticals, Ltd., Allschwil, Switzerland (F.L., U.R.).
  • Kim MS; Department of Cancer Biology, Metastasis Research Laboratory, The University of Texas MD Anderson Cancer Center, Houston, Texas (H.J.L., M.H., S.-J.K., H.Y., M.S.K., J.H., R.R.L., I.J.F.); Actelion Pharmaceuticals, Ltd., Allschwil, Switzerland (F.L., U.R.).
  • He J; Department of Cancer Biology, Metastasis Research Laboratory, The University of Texas MD Anderson Cancer Center, Houston, Texas (H.J.L., M.H., S.-J.K., H.Y., M.S.K., J.H., R.R.L., I.J.F.); Actelion Pharmaceuticals, Ltd., Allschwil, Switzerland (F.L., U.R.).
  • Langley RR; Department of Cancer Biology, Metastasis Research Laboratory, The University of Texas MD Anderson Cancer Center, Houston, Texas (H.J.L., M.H., S.-J.K., H.Y., M.S.K., J.H., R.R.L., I.J.F.); Actelion Pharmaceuticals, Ltd., Allschwil, Switzerland (F.L., U.R.).
  • Lehembre F; Department of Cancer Biology, Metastasis Research Laboratory, The University of Texas MD Anderson Cancer Center, Houston, Texas (H.J.L., M.H., S.-J.K., H.Y., M.S.K., J.H., R.R.L., I.J.F.); Actelion Pharmaceuticals, Ltd., Allschwil, Switzerland (F.L., U.R.).
  • Regenass U; Department of Cancer Biology, Metastasis Research Laboratory, The University of Texas MD Anderson Cancer Center, Houston, Texas (H.J.L., M.H., S.-J.K., H.Y., M.S.K., J.H., R.R.L., I.J.F.); Actelion Pharmaceuticals, Ltd., Allschwil, Switzerland (F.L., U.R.).
  • Fidler IJ; Department of Cancer Biology, Metastasis Research Laboratory, The University of Texas MD Anderson Cancer Center, Houston, Texas (H.J.L., M.H., S.-J.K., H.Y., M.S.K., J.H., R.R.L., I.J.F.); Actelion Pharmaceuticals, Ltd., Allschwil, Switzerland (F.L., U.R.).
Neuro Oncol ; 18(4): 486-96, 2016 Apr.
Article em En | MEDLINE | ID: mdl-26995790

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Sulfonamidas / Neoplasias da Mama / Paclitaxel / Receptores de Endotelina / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Sulfonamidas / Neoplasias da Mama / Paclitaxel / Receptores de Endotelina / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article