Fetal and neonatal abnormalities due to congenital rubella syndrome: a review of literature.
J Matern Fetal Neonatal Med
; 30(3): 274-278, 2017 Feb.
Article
em En
| MEDLINE
| ID: mdl-27002428
ABSTRACT
OBJECTIVE:
Rubella virus infection during the first trimester of pregnancy can cause congenital rubella syndrome (CRS). We aimed to describe the abnormalities in order to define the ultrasound features to look for when performing prenatal scans. The goal of this review is to focus specifically on the signs of CRS accessible to prenatal diagnosis.METHODS:
We analyzed every case of CRS described before and/or after birth that we identified in the Pubmed database and classified them as accessible or not to prenatal diagnosis.RESULTS:
The most frequently reported malformations accessible to prenatal diagnosis were cardiac septal defects, pulmonary artery stenosis, microcephaly, cataract, microphtalmia, and hepatosplenomegaly.CONCLUSION:
This extensive literature review shows that the ultrasound features of CRS are not well known, even though rubella was the first teratogenic virus described. This review will help clinicians in the management of rubella during pregnancy by clarifying the findings to be sought.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Síndrome da Rubéola Congênita
/
Ultrassonografia Pré-Natal
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
/
Systematic_reviews
Limite:
Female
/
Humans
/
Newborn
/
Pregnancy
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article