A Practical Guide to The Cancer Genome Atlas (TCGA).

Wang, Zhining; Jensen, Mark A; Zenklusen, Jean Claude

Wang, Zhining; Jensen, Mark A; Zenklusen, Jean Claude.

Afiliação

Wang Z; Center for Cancer Genomics, National Cancer Institute, National Institutes of Health, 31 Center Drive, Bethesda, MD, USA. zhining.wang@nih.gov.
Jensen MA; Research Administration Directorate, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, 8560 Progress Drive, Frederick, 21701, MD, USA.
Zenklusen JC; Center for Cancer Genomics, National Cancer Institute, National Institutes of Health, 31 Center Drive, Bethesda, MD, USA.

Methods Mol Biol ; 1418: 111-41, 2016.

Article em En | MEDLINE | ID: mdl-27008012

RESUMO

The Cancer Genome Atlas (TCGA) is one of the most ambitious and successful cancer genomics programs to date. The TCGA program has generated, analyzed, and made available genomic sequence, expression, methylation, and copy number variation data on over 11,000 individuals who represent over 30 different types of cancer. This chapter provides a brief overview of the TCGA program and detailed instructions and tips for investigators on how to find, access, and download this data.

Assuntos

Biologia Computacional/métodos; Bases de Dados Genéticas; Genômica/métodos; Neoplasias/genética; Animais; Humanos; Neoplasias/metabolismo; Software; Navegador

Palavras-chave

Cancer genomics; Copy number; Methylation; Mutation; Next-generation sequencing; Proteomics; TCGA; The Cancer Genome Atlas; Transcriptome; miRNA

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biologia Computacional / Genômica / Bases de Dados Genéticas / Neoplasias Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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