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Design, synthesis and evaluation of molecularly targeted hypoxia-activated prodrugs.
O'Connor, Liam J; Cazares-Körner, Cindy; Saha, Jaideep; Evans, Charles N G; Stratford, Michael R L; Hammond, Ester M; Conway, Stuart J.
Afiliação
  • O'Connor LJ; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, UK.
  • Cazares-Körner C; Department of Oncology, Cancer Research UK (CRUK)/Medical Research Council (MRC) Institute for Radiation Oncology, University of Oxford, Oxford, UK.
  • Saha J; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, UK.
  • Evans CN; Department of Oncology, Cancer Research UK (CRUK)/Medical Research Council (MRC) Institute for Radiation Oncology, University of Oxford, Oxford, UK.
  • Stratford MR; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, UK.
  • Hammond EM; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, UK.
  • Conway SJ; Department of Oncology, Cancer Research UK (CRUK)/Medical Research Council (MRC) Institute for Radiation Oncology, University of Oxford, Oxford, UK.
Nat Protoc ; 11(4): 781-94, 2016 Apr.
Article em En | MEDLINE | ID: mdl-27010756
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Pró-Fármacos / Inibidores Enzimáticos / Hipóxia / Metronidazol / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Pró-Fármacos / Inibidores Enzimáticos / Hipóxia / Metronidazol / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article