Targeting of exon VI-skipping human RGR-opsin to the plasma membrane of pigment epithelium and co-localization with terminal complement complex C5b-9.

Kochounian, Harold; Zhang, Zhaoxia; Spee, Christine; Hinton, David R; Fong, Henry K W

Kochounian, Harold; Zhang, Zhaoxia; Spee, Christine; Hinton, David R; Fong, Henry K W.

Afiliação

Kochounian H; Doheny Eye Institute, Los Angeles, CA.
Zhang Z; Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA; USC Eye Institute, Keck School of Medicine of the University of Southern California, Los Angeles, CA.
Spee C; Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA.
Hinton DR; Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA; Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, CA; USC Eye Institute, Keck School of Medicine of the University of Southern Califor
Fong HK; Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA; Department of Molecular Microbiology and Immunology, Keck School of Medicine of the University of Southern California, Los Angeles, CA; USC Eye Institute, Keck School of Medicine of the Un

Mol Vis ; 22: 213-23, 2016.

Article em En | MEDLINE | ID: mdl-27011730

Assuntos

Processamento Alternativo/fisiologia; Membrana Celular/metabolismo; Complexo de Ataque à Membrana do Sistema Complemento/metabolismo; Proteínas do Olho/metabolismo; Opsinas/metabolismo; Receptores Acoplados a Proteínas G/metabolismo; Epitélio Pigmentado da Retina/metabolismo; Idoso; Western Blotting; Lâmina Basilar da Corioide/metabolismo; Células Cultivadas; Éxons/genética; Proteínas do Olho/genética; Feminino; Técnica Indireta de Fluorescência para Anticorpo; Vetores Genéticos; Humanos; Masculino; Proteína Cofatora de Membrana/metabolismo; Microscopia Confocal; Pessoa de Meia-Idade; RNA Mensageiro/genética; Receptores Acoplados a Proteínas G/genética; Doadores de Tecidos; Transfecção; Vitronectina/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Complexo de Ataque à Membrana do Sistema Complemento / Membrana Celular / Processamento Alternativo / Receptores Acoplados a Proteínas G / Proteínas do Olho / Epitélio Pigmentado da Retina / Opsinas Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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