Gracilone, a new sesquiterpene lactone from Tanacetum gracile (Tansies).
Nat Prod Res
; 30(20): 2291-8, 2016 Oct.
Article
em En
| MEDLINE
| ID: mdl-27018200
ABSTRACT
The methanolic extract of the Tanacetum gracile afforded the isolation of new sesquiterpene lactone, named gracilone (1) along with four known compounds as 14α-taraxeran-3-one (2), 14α-taraxeran-3-ol (3), apigenin (4) and ß-sitosterol (5). The structure of compound 1 was elucidated on the basis of 1D, 2D NMR and MS spectroscopic analysis. Antimicrobial, antioxidant and anticancer activities of all compounds were evaluated, from which gracilone (1) showed a moderate antibacterial activity, while apigenin (4) showed comparatively more antibacterial activity against both gram-positive and gram-negative tested strains.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Sesquiterpenos
/
Tanacetum
/
Lactonas
/
Antibacterianos
/
Antineoplásicos Fitogênicos
/
Antioxidantes
Limite:
Humans
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article