An Approximate Markov Model for the Wright-Fisher Diffusion and Its Application to Time Series Data.

Ferrer-Admetlla, Anna; Leuenberger, Christoph; Jensen, Jeffrey D; Wegmann, Daniel

Ferrer-Admetlla, Anna; Leuenberger, Christoph; Jensen, Jeffrey D; Wegmann, Daniel.

Afiliação

Ferrer-Admetlla A; Department of Biology, University, of Fribourg, 1700 Fribourg Switzerland Department of Life Science, Ecole Polytechnique Federal de Lausanne, 1015 Switzerland Swiss Institute of Bioinformatics, 1700 Fribourg, Switzerland.
Leuenberger C; Department of Mathematics, University, of Fribourg, 1700 Fribourg Switzerland.
Jensen JD; Department of Life Science, Ecole Polytechnique Federal de Lausanne, 1015 Switzerland Swiss Institute of Bioinformatics, 1700 Fribourg, Switzerland.
Wegmann D; Department of Biology, University, of Fribourg, 1700 Fribourg Switzerland Swiss Institute of Bioinformatics, 1700 Fribourg, Switzerland daniel.wegmann@unifr.ch.

Genetics ; 203(2): 831-46, 2016 06.

Article em En | MEDLINE | ID: mdl-27038112

Assuntos

Farmacorresistência Viral/genética; Evolução Molecular; Modelos Genéticos; Orthomyxoviridae/genética; Cadeias de Markov; Orthomyxoviridae/efeitos dos fármacos; Seleção Genética

Palavras-chave

WrightFisher model; diffusion approximation; discrete Markov model; hidden Markov model; time-series data

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Orthomyxoviridae / Evolução Molecular / Farmacorresistência Viral / Modelos Genéticos Tipo de estudo: Health_economic_evaluation / Prognostic_studies Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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