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Long antibody HCDR3s from HIV-naïve donors presented on a PG9 neutralizing antibody background mediate HIV neutralization.
Willis, Jordan R; Finn, Jessica A; Briney, Bryan; Sapparapu, Gopal; Singh, Vidisha; King, Hannah; LaBranche, Celia C; Montefiori, David C; Meiler, Jens; Crowe, James E.
Afiliação
  • Willis JR; Chemical and Physical Biology Program, Vanderbilt University, Nashville, TN 37232; Center for Structural Biology, Vanderbilt University, Nashville, TN 37232; Vanderbilt Vaccine Center, Vanderbilt University, Nashville, TN 37232;
  • Finn JA; Center for Structural Biology, Vanderbilt University, Nashville, TN 37232; Vanderbilt Vaccine Center, Vanderbilt University, Nashville, TN 37232; Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN 37232;
  • Briney B; Vanderbilt Vaccine Center, Vanderbilt University, Nashville, TN 37232; Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN 37232;
  • Sapparapu G; Vanderbilt Vaccine Center, Vanderbilt University, Nashville, TN 37232; Department of Pediatrics, Vanderbilt University, Nashville, TN 37232;
  • Singh V; Vanderbilt Vaccine Center, Vanderbilt University, Nashville, TN 37232;
  • King H; Vanderbilt Vaccine Center, Vanderbilt University, Nashville, TN 37232;
  • LaBranche CC; Department of Surgery, Duke University Medical Center, Durham, NC 27710;
  • Montefiori DC; Department of Surgery, Duke University Medical Center, Durham, NC 27710;
  • Meiler J; Chemical and Physical Biology Program, Vanderbilt University, Nashville, TN 37232; Center for Structural Biology, Vanderbilt University, Nashville, TN 37232; Department of Chemistry, Vanderbilt University, Nashville, TN 37232; Institute for Chemical Biology, Vanderbilt University, Nashville, TN 3723
  • Crowe JE; Chemical and Physical Biology Program, Vanderbilt University, Nashville, TN 37232; Vanderbilt Vaccine Center, Vanderbilt University, Nashville, TN 37232; Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN 37232; Department of Pediatrics, Vanderbilt University
Proc Natl Acad Sci U S A ; 113(16): 4446-51, 2016 Apr 19.
Article em En | MEDLINE | ID: mdl-27044078
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos Anti-HIV / Proteína gp120 do Envelope de HIV / HIV-1 / Cadeias Pesadas de Imunoglobulinas / Regiões Determinantes de Complementaridade / Anticorpos Neutralizantes Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos Anti-HIV / Proteína gp120 do Envelope de HIV / HIV-1 / Cadeias Pesadas de Imunoglobulinas / Regiões Determinantes de Complementaridade / Anticorpos Neutralizantes Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article