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Hypothesis testing for differentially correlated features.
Sheng, Elisa; Witten, Daniela; Zhou, Xiao-Hua.
Afiliação
  • Sheng E; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Witten D; Department of Biostatistics, University of Washington, Seattle, Washington, USA and Department of Statistics, University of Washington, Seattle, Washington, USA.
  • Zhou XH; Department of Biostatistics, University of Washington, Seattle, Washington, USA and Veterans Affairs Seattle Medical Center, Seattle, Washington, USA azhou@uw.edu.
Biostatistics ; 17(4): 677-91, 2016 10.
Article em En | MEDLINE | ID: mdl-27044327
In a multivariate setting, we consider the task of identifying features whose correlations with the other features differ across conditions. Such correlation shifts may occur independently of mean shifts, or differences in the means of the individual features across conditions. Previous approaches for detecting correlation shifts consider features simultaneously, by computing a correlation-based test statistic for each feature. However, since correlations involve two features, such approaches do not lend themselves to identifying which feature is the culprit. In this article, we instead consider a serial testing approach, by comparing columns of the sample correlation matrix across two conditions, and removing one feature at a time. Our method provides a novel perspective and favorable empirical results compared with competing approaches.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Projetos de Pesquisa / Bioestatística / Interpretação Estatística de Dados / Modelos Teóricos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Projetos de Pesquisa / Bioestatística / Interpretação Estatística de Dados / Modelos Teóricos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article