Complete Sequence of the FII Plasmid p42-2, Carrying blaCTX-M-55, oqxAB, fosA3, and floR from Escherichia coli.
Antimicrob Agents Chemother
; 60(7): 4336-8, 2016 07.
Article
em En
| MEDLINE
| ID: mdl-27067314
ABSTRACT
We sequenced a novel conjugative multidrug resistance IncF plasmid, p42-2, isolated from Escherichia coli strain 42-2, previously identified in China. p42-2 is 106,886 bp long, composed of a typical IncFII-type backbone (â¼54 kb) and one distinct acquired DNA region spanning â¼53 kb, harboring 12 antibiotic resistance genes [blaCTX-M-55, oqxA, oqxB, fosA3, floR, tetA(A), tetA(R), strA, strB, sul2, aph(3')-II, and ΔblaTEM-1]. The spread of these multidrug resistance determinants on the same plasmid is of great concern and, because of coresistance to antibiotics from different classes, is therapeutically challenging.
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Base de dados:
MEDLINE
Assunto principal:
Beta-Lactamases
/
Escherichia coli
/
Antibacterianos
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article