Cigarette smoke extracts induced the colon cancer migration via regulating epithelial mesenchymal transition and metastatic genes in human colon cancer cells.

Kim, Cho-Won; Go, Ryeo-Eun; Lee, Hae-Miru; Hwang, Kyung-A; Lee, Kyuhong; Kim, Bumseok; Lee, Moo-Yeol; Choi, Kyung-Chul

Kim, Cho-Won; Go, Ryeo-Eun; Lee, Hae-Miru; Hwang, Kyung-A; Lee, Kyuhong; Kim, Bumseok; Lee, Moo-Yeol; Choi, Kyung-Chul.

Afiliação

Kim CW; Laboratory of Biochemistry and Immunology, Department of Veterinary Medicine, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.
Go RE; Laboratory of Biochemistry and Immunology, Department of Veterinary Medicine, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.
Lee HM; Laboratory of Biochemistry and Immunology, Department of Veterinary Medicine, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.
Hwang KA; Laboratory of Biochemistry and Immunology, Department of Veterinary Medicine, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.
Lee K; Inhalation Toxicology Center, Jeonbuk Department of Non-Human Primate, Korea Institute of Toxicology, Jeonbuk, Republic of Korea.
Kim B; Biosafety Research Institute and Laboratory of Pathology (BK21 Plus Program), Department of Veterinary Medicine, College of Veterinary Medicine, Chonbuk National University, Iksan, Republic of Korea.
Lee MY; Department of Pharmaceutical Sciences, College of Pharmacy, Dongguk University, Goyang, Gyeonggi-Do, Republic of Korea.
Choi KC; Laboratory of Biochemistry and Immunology, Department of Veterinary Medicine, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.

Environ Toxicol ; 32(2): 690-704, 2017 Feb.

Article em En | MEDLINE | ID: mdl-27087172

Assuntos

Movimento Celular/efeitos dos fármacos; Transição Epitelial-Mesenquimal; Fumar/efeitos adversos; Antígenos CD; Apoptose/efeitos dos fármacos; Caderinas/genética; Caderinas/metabolismo; Catepsina D/metabolismo; Ciclo Celular; Linhagem Celular Tumoral; Proliferação de Células/efeitos dos fármacos; Sobrevivência Celular/efeitos dos fármacos; Neoplasias do Colo/patologia; Ciclina D1/genética; Ciclina D1/metabolismo; Inibidor de Quinase Dependente de Ciclina p21/genética; Inibidor de Quinase Dependente de Ciclina p21/metabolismo; Células Epiteliais/efeitos dos fármacos; Expressão Gênica/efeitos dos fármacos; Humanos; Metástase Neoplásica; Fumaça/efeitos adversos; Proteína Supressora de Tumor p53/genética; Proteína Supressora de Tumor p53/metabolismo

Palavras-chave

apoptosis; cell cycle; cigarette smoke extract; colon cancer cells; metastasis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fumar / Movimento Celular / Transição Epitelial-Mesenquimal Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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