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Sparsity-Based Pixel Super Resolution for Lens-Free Digital In-line Holography.
Song, Jun; Leon Swisher, Christine; Im, Hyungsoon; Jeong, Sangmoo; Pathania, Divya; Iwamoto, Yoshiko; Pivovarov, Misha; Weissleder, Ralph; Lee, Hakho.
Afiliação
  • Song J; Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
  • Leon Swisher C; School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, United States of America.
  • Im H; Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
  • Jeong S; Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
  • Pathania D; Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
  • Iwamoto Y; Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
  • Pivovarov M; Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
  • Weissleder R; Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
  • Lee H; Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Sci Rep ; 6: 24681, 2016 Apr 21.
Article em En | MEDLINE | ID: mdl-27098438
Lens-free digital in-line holography (LDIH) is a promising technology for portable, wide field-of-view imaging. Its resolution, however, is limited by the inherent pixel size of an imaging device. Here we present a new computational approach to achieve sub-pixel resolution for LDIH. The developed method is a sparsity-based reconstruction with the capability to handle the non-linear nature of LDIH. We systematically characterized the algorithm through simulation and LDIH imaging studies. The method achieved the spatial resolution down to one-third of the pixel size, while requiring only single-frame imaging without any hardware modifications. This new approach can be used as a general framework to enhance the resolution in nonlinear holographic systems.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Holografia Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Holografia Idioma: En Ano de publicação: 2016 Tipo de documento: Article