Comparative characterisation of two nitroreductases from Giardia lamblia as potential activators of nitro compounds.

Müller, Joachim; Rout, Samuel; Leitsch, David; Vaithilingam, Jathana; Hehl, Adrian; Müller, Norbert

Müller, Joachim; Rout, Samuel; Leitsch, David; Vaithilingam, Jathana; Hehl, Adrian; Müller, Norbert.

Afiliação

Müller J; Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland.
Rout S; Institute of Parasitology, Eukaryotic Microbiology, University of Zürich, Winterthurerstrasse 266a, CH-8057 Zürich, Switzerland.
Leitsch D; Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland.
Vaithilingam J; Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland.
Hehl A; Institute of Parasitology, Eukaryotic Microbiology, University of Zürich, Winterthurerstrasse 266a, CH-8057 Zürich, Switzerland.
Müller N; Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland.

Int J Parasitol Drugs Drug Resist ; 5(2): 37-43, 2015 Aug.

Article em En | MEDLINE | ID: mdl-27099829

Assuntos

Giardia lamblia/enzimologia; Nitrocompostos/metabolismo; Nitrorredutases/metabolismo; Ativação Metabólica; Escherichia coli/genética; NAD/metabolismo; NAD(P)H Desidrogenase (Quinona)/metabolismo; Proteínas Recombinantes/biossíntese

Palavras-chave

Functional assays; Mode of action of nitro compounds; Nitroreduction

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nitrorredutases / Giardia lamblia / Nitrocompostos Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nitrorredutases / Giardia lamblia / Nitrocompostos Idioma: En Ano de publicação: 2015 Tipo de documento: Article