Intra- and Intermolecular Nickel-Catalyzed Reductive Cross-Electrophile Coupling Reactions of Benzylic Esters with Aryl Halides.
Angew Chem Int Ed Engl
; 55(23): 6730-3, 2016 06 01.
Article
em En
| MEDLINE
| ID: mdl-27099968
ABSTRACT
Nickel-catalyzed cross-electrophile coupling reactions of benzylic esters and aryl halides have been developed. Both inter- and intramolecular variants proceed under mild reaction conditions. A range of heterocycles and functional groups are tolerated under the reaction conditions. Additionally, the first example of a stereospecific cross-electrophile coupling of a secondary benzylic ester is described.
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MEDLINE
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En
Ano de publicação:
2016
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Article