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Digital PCR methods improve detection sensitivity and measurement precision of low abundance mtDNA deletions.
Belmonte, Frances R; Martin, James L; Frescura, Kristin; Damas, Joana; Pereira, Filipe; Tarnopolsky, Mark A; Kaufman, Brett A.
Afiliação
  • Belmonte FR; University of Pittsburgh School of Medicine, Division of Cardiology, Center for Metabolism and Mitochondrial Medicine and Vascular Medicine Institute, Pittsburgh, PA, 15261, United States.
  • Martin JL; University of Pittsburgh School of Medicine, Division of Cardiology, Center for Metabolism and Mitochondrial Medicine and Vascular Medicine Institute, Pittsburgh, PA, 15261, United States.
  • Frescura K; Departments of Pediatrics and Medicine, McMaster University Medical Center, Hamilton, ON, L8N 3Z5, Canada.
  • Damas J; Department of Comparative Biomedical Sciences, Royal Veterinary College, London, UK.
  • Pereira F; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Porto, Portugal.
  • Tarnopolsky MA; Departments of Pediatrics and Medicine, McMaster University Medical Center, Hamilton, ON, L8N 3Z5, Canada.
  • Kaufman BA; University of Pittsburgh School of Medicine, Division of Cardiology, Center for Metabolism and Mitochondrial Medicine and Vascular Medicine Institute, Pittsburgh, PA, 15261, United States.
Sci Rep ; 6: 25186, 2016 04 28.
Article em En | MEDLINE | ID: mdl-27122135
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / Reação em Cadeia da Polimerase / Deleção de Sequência / Doenças Mitocondriais Tipo de estudo: Diagnostic_studies / Evaluation_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / Reação em Cadeia da Polimerase / Deleção de Sequência / Doenças Mitocondriais Tipo de estudo: Diagnostic_studies / Evaluation_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article