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Discovery of 5-(methylthio)pyrimidine derivatives as L858R/T790M mutant selective epidermal growth factor receptor (EGFR) inhibitors.
Xiao, Qiang; Qu, Rong; Gao, Dingding; Yan, Qi; Tong, Linjiang; Zhang, Wei; Ding, Jian; Xie, Hua; Li, Yingxia.
Afiliação
  • Xiao Q; School of Pharmacy, Fudan University, Shanghai 201203, China.
  • Qu R; Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Gao D; School of Pharmacy, Fudan University, Shanghai 201203, China.
  • Yan Q; School of Pharmacy, Fudan University, Shanghai 201203, China.
  • Tong L; Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Zhang W; School of Pharmacy, Fudan University, Shanghai 201203, China.
  • Ding J; Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Xie H; Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. Electronic address: hxie@simm.ac.cn.
  • Li Y; School of Pharmacy, Fudan University, Shanghai 201203, China. Electronic address: liyx417@fudan.edu.cn.
Bioorg Med Chem ; 24(12): 2673-80, 2016 06 15.
Article em En | MEDLINE | ID: mdl-27131639
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Inibidores de Proteínas Quinases / Receptores ErbB / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Inibidores de Proteínas Quinases / Receptores ErbB / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article