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Inhibition of DPP4 activity in humans establishes its in vivo role in CXCL10 post-translational modification: prospective placebo-controlled clinical studies.
Decalf, Jérémie; Tarbell, Kristin V; Casrouge, Armanda; Price, Jeffrey D; Linder, Grace; Mottez, Estelle; Sultanik, Philippe; Mallet, Vincent; Pol, Stanislas; Duffy, Darragh; Albert, Matthew L.
Afiliação
  • Decalf J; The Laboratory of Dendritic Cell Immunobiology, Institut Pasteur, Paris, France INSERM U818, Paris, France.
  • Tarbell KV; Diabetes Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Casrouge A; The Laboratory of Dendritic Cell Immunobiology, Institut Pasteur, Paris, France INSERM U818, Paris, France.
  • Price JD; Diabetes Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Linder G; Diabetes Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Mottez E; Center for Human Immunology, Institut Pasteur, Paris, France.
  • Sultanik P; Département d'Hépatologie, AP-HP, Hôpital Cochin, Université Paris Descartes, INSERM UMS20, Institut Pasteur, Paris, France.
  • Mallet V; Département d'Hépatologie, AP-HP, Hôpital Cochin, Université Paris Descartes, INSERM UMS20, Institut Pasteur, Paris, France.
  • Pol S; Département d'Hépatologie, AP-HP, Hôpital Cochin, Université Paris Descartes, INSERM UMS20, Institut Pasteur, Paris, France.
  • Duffy D; The Laboratory of Dendritic Cell Immunobiology, Institut Pasteur, Paris, France INSERM U818, Paris, France Center for Human Immunology, Institut Pasteur, Paris, France darragh.duffy@pasteur.fr albertm@pasteur.fr.
  • Albert ML; The Laboratory of Dendritic Cell Immunobiology, Institut Pasteur, Paris, France INSERM U818, Paris, France Center for Human Immunology, Institut Pasteur, Paris, France Department of Cancer Immunotherapy, Genentech, South San Francisco, CA, USA darragh.duffy@pasteur.fr albertm@pasteur.fr.
EMBO Mol Med ; 8(6): 679-83, 2016 06.
Article em En | MEDLINE | ID: mdl-27137491
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Processamento de Proteína Pós-Traducional / Dipeptidil Peptidase 4 / Quimiocina CXCL10 / Inibidores da Dipeptidil Peptidase IV / Fosfato de Sitagliptina Tipo de estudo: Clinical_trials / Observational_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Processamento de Proteína Pós-Traducional / Dipeptidil Peptidase 4 / Quimiocina CXCL10 / Inibidores da Dipeptidil Peptidase IV / Fosfato de Sitagliptina Tipo de estudo: Clinical_trials / Observational_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article