Tumor Necrosis Factor-stimulated Gene 6 (TSG-6)-mediated Interactions with the Inter-&#945;-inhibitor Heavy Chain 5 Facilitate Tumor Growth Factor ß1 (TGFß1)-dependent Fibroblast to Myofibroblast Differentiation.

Martin, John; Midgley, Adam; Meran, Soma; Woods, Emma; Bowen, Timothy; Phillips, Aled O; Steadman, Robert

Tumor Necrosis Factor-stimulated Gene 6 (TSG-6)-mediated Interactions with the Inter-α-inhibitor Heavy Chain 5 Facilitate Tumor Growth Factor ß1 (TGFß1)-dependent Fibroblast to Myofibroblast Differentiation.

Martin, John; Midgley, Adam; Meran, Soma; Woods, Emma; Bowen, Timothy; Phillips, Aled O; Steadman, Robert.

Afiliação

Martin J; From the Department of Nephrology, Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine and Cardiff Institute of Tissue Engineering and Repair, Heath Park, Cardiff CF14 4XN, United Kingdom.
Midgley A; From the Department of Nephrology, Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine and Cardiff Institute of Tissue Engineering and Repair, Heath Park, Cardiff CF14 4XN, United Kingdom.
Meran S; From the Department of Nephrology, Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine and Cardiff Institute of Tissue Engineering and Repair, Heath Park, Cardiff CF14 4XN, United Kingdom.
Woods E; From the Department of Nephrology, Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine and Cardiff Institute of Tissue Engineering and Repair, Heath Park, Cardiff CF14 4XN, United Kingdom.
Bowen T; From the Department of Nephrology, Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine and Cardiff Institute of Tissue Engineering and Repair, Heath Park, Cardiff CF14 4XN, United Kingdom.
Phillips AO; From the Department of Nephrology, Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine and Cardiff Institute of Tissue Engineering and Repair, Heath Park, Cardiff CF14 4XN, United Kingdom.
Steadman R; From the Department of Nephrology, Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine and Cardiff Institute of Tissue Engineering and Repair, Heath Park, Cardiff CF14 4XN, United Kingdom steadmanr@cf.ac.uk.

J Biol Chem ; 291(26): 13789-801, 2016 Jun 24.

Article em En | MEDLINE | ID: mdl-27143355

Assuntos

Moléculas de Adesão Celular/metabolismo; Diferenciação Celular/fisiologia; Miofibroblastos/metabolismo; Proteínas Secretadas Inibidoras de Proteinases/metabolismo; Fator de Crescimento Transformador beta1/metabolismo; Actinas/genética; Actinas/metabolismo; alfa-Globulinas/farmacologia; Anticorpos Monoclonais Murinos/farmacologia; Moléculas de Adesão Celular/genética; Diferenciação Celular/efeitos dos fármacos; Linhagem Celular; Receptores ErbB/genética; Receptores ErbB/metabolismo; Regulação da Expressão Gênica/efeitos dos fármacos; Humanos; Receptores de Hialuronatos/farmacologia; Miofibroblastos/citologia; Fator de Crescimento Transformador beta1/genética

Palavras-chave

fibroblast; fibrosis; hyaluronan; myofibroblast; transforming growth factor beta (TGF-B); tumor necrosis factor gene 6

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Moléculas de Adesão Celular / Diferenciação Celular / Fator de Crescimento Transformador beta1 / Proteínas Secretadas Inibidoras de Proteinases / Miofibroblastos Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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