A case of meningococcal meningitis that was difficult to treat owing to concurrent ventriculitis.
Rinsho Shinkeigaku
; 56(5): 344-7, 2016 05 31.
Article
em Ja
| MEDLINE
| ID: mdl-27151225
ABSTRACT
A 64-year-old male came to our hospital emergency department with fever and consciousness disturbance. Culture tests of blood and spinal fluid samples revealed meningococci (Neisseria meningitidis), and we made a diagnosis of meningococcal meningitis. Brain magnetic resonance imaging (MRI) findings revealed ventriculitis. Ceftriaxone was administered for 17 days, however, relapse was noted after that was discontinued, with neutropenia and renal impairment thought to be adverse reactions to the beta-lactam antibiotic. Hence, treatment was switched to oral administration of moxifloxacin for a total of 12 weeks, including in an outpatient setting. After moxifloxacin was discontinued, no side effects or relapse were seen, and treatment was ended. Although antibacterial agents generally show favorable effects for meningococcal meningitis, we consider that sufficient antimicrobial therapy is difficult in cases complicated with ventriculitis.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ventriculite Cerebral
/
Meningite Meningocócica
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
/
Male
/
Middle aged
Idioma:
Ja
Ano de publicação:
2016
Tipo de documento:
Article