Growth Arrest-Specific 6 (GAS6) Promotes Prostate Cancer Survival by G<sub>1</sub> Arrest/S Phase Delay and Inhibition of Apoptosis During Chemotherapy in Bone Marrow.

Lee, Eunsohl; Decker, Ann M; Cackowski, Frank C; Kana, Lulia A; Yumoto, Kenji; Jung, Younghun; Wang, Jingcheng; Buttitta, Laura; Morgan, Todd M; Taichman, Russell S

Growth Arrest-Specific 6 (GAS6) Promotes Prostate Cancer Survival by G₁ Arrest/S Phase Delay and Inhibition of Apoptosis During Chemotherapy in Bone Marrow.

Lee, Eunsohl; Decker, Ann M; Cackowski, Frank C; Kana, Lulia A; Yumoto, Kenji; Jung, Younghun; Wang, Jingcheng; Buttitta, Laura; Morgan, Todd M; Taichman, Russell S.

Afiliação

Lee E; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, 48109, Michigan.
Decker AM; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, 48109, Michigan.
Cackowski FC; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, 48109, Michigan.
Kana LA; Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, 48109, Michigan.
Yumoto K; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, 48109, Michigan.
Jung Y; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, 48109, Michigan.
Wang J; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, 48109, Michigan.
Buttitta L; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, 48109, Michigan.
Morgan TM; Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, 48109, Michigan.
Taichman RS; Department of Urology, University of Michigan School of Medicine, Ann Arbor, 48109, Michigan.

J Cell Biochem ; 117(12): 2815-2824, 2016 12.

Article em En | MEDLINE | ID: mdl-27153245

Assuntos

Apoptose/efeitos dos fármacos; Medula Óssea/efeitos dos fármacos; Fase G1/efeitos dos fármacos; Peptídeos e Proteínas de Sinalização Intercelular/metabolismo; Peptídeos e Proteínas de Sinalização Intercelular/fisiologia; Neoplasias da Próstata/patologia; Fase S/efeitos dos fármacos; Animais; Antineoplásicos/farmacologia; Western Blotting; Proteínas de Ciclo Celular/genética; Proteínas de Ciclo Celular/metabolismo; Proliferação de Células/efeitos dos fármacos; Células Cultivadas; Docetaxel; Humanos; Peptídeos e Proteínas de Sinalização Intercelular/genética; Masculino; Camundongos; Camundongos Knockout; Osteoblastos/citologia; Osteoblastos/efeitos dos fármacos; Osteoblastos/metabolismo; Neoplasias da Próstata/tratamento farmacológico; Neoplasias da Próstata/metabolismo; RNA Mensageiro/genética; Reação em Cadeia da Polimerase em Tempo Real; Reação em Cadeia da Polimerase Via Transcriptase Reversa; Taxoides/farmacologia

Palavras-chave

APOPTOTIC PATHWAY; BONE MARROW; DOCETAXEL; G1 ARREST/S PHASE DELAY; GAS6; PROSTATE CANCER

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Medula Óssea / Fase G1 / Fase S / Apoptose / Peptídeos e Proteínas de Sinalização Intercelular Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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