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Killing two birds with one stone: Model plant systems as a tool to teach the fundamental concepts of gene expression while analyzing biological data.
Makarevitch, Irina; Martinez-Vaz, Betsy.
Afiliação
  • Makarevitch I; Department of Biology, Hamline University, Saint Paul, MN 55104, United States. Electronic address: imakarevitch01@hamline.edu.
  • Martinez-Vaz B; Department of Biology, Hamline University, Saint Paul, MN 55104, United States.
Biochim Biophys Acta Gene Regul Mech ; 1860(1): 166-173, 2017 Jan.
Article em En | MEDLINE | ID: mdl-27155065
ABSTRACT
Plants are ideal systems to teach core biology concepts due to their unique physiological and developmental features. Advances in DNA sequencing technology and genomics have allowed scientists to generate genome sequences and transcriptomics data for numerous model plant species. This information is publicly available and presents a valuable tool to introduce undergraduate students to the fundamental concepts of gene expression in the context of modern quantitative biology and bioinformatics. Modern biology classrooms must provide authentic research experiences to allow developing core competencies such as scientific inquiry, critical interpretation of experimental results, and quantitative analyses of large dataset using computational approaches. Recent educational research has shown that undergraduate students struggle when connecting gene expression concepts to classic genetics, phenotypic analyses, and overall flow of biological information in living organisms, suggesting that novel approaches are necessary to enhance learning of gene expression and regulation. This review describes different strategies and resources available to instructors willing to incorporate authentic research experiences, genomic tools, and bioinformatics analyses when teaching transcriptional regulation and gene expression in undergraduate courses. A variety of laboratory exercises and pedagogy materials developed to teach gene expression using plants are discussed. This article is part of a Special Issue entitled Plant Gene Regulatory Mechanisms and Networks, edited by Dr. Erich Grotewold and Dr. Nathan Springer.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plantas / Expressão Gênica / Genoma de Planta / Regulação da Expressão Gênica de Plantas Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plantas / Expressão Gênica / Genoma de Planta / Regulação da Expressão Gênica de Plantas Idioma: En Ano de publicação: 2017 Tipo de documento: Article