tRNAscan-SE On-line: integrating search and context for analysis of transfer RNA genes.
Nucleic Acids Res
; 44(W1): W54-7, 2016 07 08.
Article
em En
| MEDLINE
| ID: mdl-27174935
ABSTRACT
High-throughput genome sequencing continues to grow the need for rapid, accurate genome annotation and tRNA genes constitute the largest family of essential, ever-present non-coding RNA genes. Newly developed tRNAscan-SE 2.0 has advanced the state-of-the-art methodology in tRNA gene detection and functional prediction, captured by rich new content of the companion Genomic tRNA Database. Previously, web-server tRNA detection was isolated from knowledge of existing tRNAs and their annotation. In this update of the tRNAscan-SE On-line resource, we tie together improvements in tRNA classification with greatly enhanced biological context via dynamically generated links between web server search results, the most relevant genes in the GtRNAdb and interactive, rich genome context provided by UCSC genome browsers. The tRNAscan-SE On-line web server can be accessed at http//trna.ucsc.edu/tRNAscan-SE/.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Saccharomyces cerevisiae
/
Interface Usuário-Computador
/
RNA de Transferência
/
Genes Fúngicos
Limite:
Humans
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article