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A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs.
Karlas, Alexander; Berre, Stefano; Couderc, Thérèse; Varjak, Margus; Braun, Peter; Meyer, Michael; Gangneux, Nicolas; Karo-Astover, Liis; Weege, Friderike; Raftery, Martin; Schönrich, Günther; Klemm, Uwe; Wurzlbauer, Anne; Bracher, Franz; Merits, Andres; Meyer, Thomas F; Lecuit, Marc.
Afiliação
  • Karlas A; Max Planck Institute for Infection Biology, Department of Molecular Biology, Charitéplatz 1, 10117 Berlin, Germany.
  • Berre S; Steinbeis Innovation gGmbH, Center for Systems Biomedicine, Haydnallee 21, 14612 Falkensee, Germany.
  • Couderc T; Institut Pasteur, Biology of Infection Unit, 28 rue du Dr. Roux, 75015 Paris, France.
  • Varjak M; Inserm U1117, 28 rue du Dr. Roux, 75015 Paris, France.
  • Braun P; Institut Pasteur, Biology of Infection Unit, 28 rue du Dr. Roux, 75015 Paris, France.
  • Meyer M; Inserm U1117, 28 rue du Dr. Roux, 75015 Paris, France.
  • Gangneux N; Institute of Technology, University of Tartu, Nooruse 1, 50411 Tartu, Estonia.
  • Karo-Astover L; Max Planck Institute for Infection Biology, Department of Molecular Biology, Charitéplatz 1, 10117 Berlin, Germany.
  • Weege F; Steinbeis Innovation gGmbH, Center for Systems Biomedicine, Haydnallee 21, 14612 Falkensee, Germany.
  • Raftery M; Steinbeis Innovation gGmbH, Center for Systems Biomedicine, Haydnallee 21, 14612 Falkensee, Germany.
  • Schönrich G; Institut Pasteur, Biology of Infection Unit, 28 rue du Dr. Roux, 75015 Paris, France.
  • Klemm U; Inserm U1117, 28 rue du Dr. Roux, 75015 Paris, France.
  • Wurzlbauer A; Institute of Technology, University of Tartu, Nooruse 1, 50411 Tartu, Estonia.
  • Bracher F; Max Planck Institute for Infection Biology, Department of Molecular Biology, Charitéplatz 1, 10117 Berlin, Germany.
  • Merits A; Institute of Virology, Charité University Medicine, Charitéplatz 1, 10117 Berlin, Germany.
  • Meyer TF; Institute of Virology, Charité University Medicine, Charitéplatz 1, 10117 Berlin, Germany.
  • Lecuit M; Max Planck Institute for Infection Biology, Core Facility Experimental Animals, Charitéplatz 1, 10117 Berlin, Germany.
Nat Commun ; 7: 11320, 2016 05 12.
Article em En | MEDLINE | ID: mdl-27177310
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Replicação Viral / Genoma Humano / Vírus Chikungunya / RNA Interferente Pequeno Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Replicação Viral / Genoma Humano / Vírus Chikungunya / RNA Interferente Pequeno Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article