Pigment Epithelium-Derived Factor (PEDF) Protects Osteoblastic Cell Line from Glucocorticoid-Induced Apoptosis via PEDF-R.

Yao, Shengcheng; Zhang, Yingnan; Wang, Xiaoyu; Zhao, Fengchao; Sun, Maji; Zheng, Xin; Dong, Hongyan; Guo, Kaijin

Yao, Shengcheng; Zhang, Yingnan; Wang, Xiaoyu; Zhao, Fengchao; Sun, Maji; Zheng, Xin; Dong, Hongyan; Guo, Kaijin.

Afiliação

Yao S; Department of Orthopaedic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, China. surgeony@126.com.
Zhang Y; Department of Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, China. zyn_xzmc@163.com.
Wang X; Department of Thoracic Cardiovascular Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, China. wxy_xzmc@163.com.
Zhao F; Department of Orthopaedic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, China. Zhjianzh@sina.com.
Sun M; Department of Orthopaedic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, China. holycityy@126.com.
Zheng X; Department of Orthopaedic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, China. thindy1980@163.com.
Dong H; Research Facility Center for Morphology, Xuzhou Medical University, Xuzhou 221004, China. dhy@xzmc.edu.cn.
Guo K; Department of Orthopaedic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, China. kj_guoxzmc@163.com.

Int J Mol Sci ; 17(5)2016 May 13.

Article em En | MEDLINE | ID: mdl-27187377

Assuntos

Apoptose; Proteínas do Olho/metabolismo; Fatores de Crescimento Neural/metabolismo; Osteoblastos/metabolismo; Receptores de Neuropeptídeos/metabolismo; Serpinas/metabolismo; Animais; Linhagem Celular; Dexametasona/toxicidade; Proteínas do Olho/genética; Camundongos; Fatores de Crescimento Neural/genética; Osteoblastos/efeitos dos fármacos; Fosfatidilinositol 3-Quinases/metabolismo; Ligação Proteica; Proteínas Proto-Oncogênicas c-akt/metabolismo; Serpinas/genética; Transdução de Sinais

Palavras-chave

PI3K/Akt signaling; apoptosis; glucocorticoids; lysophosphatidic acid; pigment epithelium-derived factor; pigment epithelium-derived factor receptor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoblastos / Serpinas / Apoptose / Receptores de Neuropeptídeos / Proteínas do Olho / Fatores de Crescimento Neural Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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