[Potentially toxic antibiotics concentrations after administration using impregnated dressing in a severe burned patient: A case report]. / Concentrations systémiques d'antibiotiques potentiellement toxiques après administration par pansement imprégné chez un patient brûlé : à propos d'un cas clinique.
Therapie
; 71(5): 483-486, 2016 Oct.
Article
em Fr
| MEDLINE
| ID: mdl-27203156
ABSTRACT
Severe burned patients present high risk of skins infections, frequently due to Pseudomonas aeruginosa. Impregnated dressings with amikacin or colistin could be a good alternative to obtain effective concentration directly at the infected site. Therapeutic drug monitoring for these antibiotics is currently recommended after an intravenous administration to obtain effective and non-toxic plasmatic concentrations. However, data are lacking about systemic exposition and risk of toxicity after an administration with impregnated dressings. We report the case of a severe burned patient with cutaneous infection treated with amikacin and colistin impregnated dressings, for which plasmatic pharmacokinetic profiles were performed.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Bandagens
/
Infecção dos Ferimentos
/
Queimaduras
/
Antibacterianos
Tipo de estudo:
Etiology_studies
Limite:
Female
/
Humans
/
Middle aged
Idioma:
Fr
Ano de publicação:
2016
Tipo de documento:
Article