S100A1 Protein Does Not Compete with Calmodulin for Ryanodine Receptor Binding but Structurally Alters the Ryanodine Receptor·Calmodulin Complex.

Rebbeck, Robyn T; Nitu, Florentin R; Rohde, David; Most, Patrick; Bers, Donald M; Thomas, David D; Cornea, Razvan L

Rebbeck, Robyn T; Nitu, Florentin R; Rohde, David; Most, Patrick; Bers, Donald M; Thomas, David D; Cornea, Razvan L.

Afiliação

Rebbeck RT; From the Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis Minnesota 55455.
Nitu FR; From the Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis Minnesota 55455.
Rohde D; the Center for Molecular and Translational Cardiology, Department of Internal Medicine III, University of Heidelberg, INF 410, 69120, Heidelberg, Germany, and.
Most P; the Center for Molecular and Translational Cardiology, Department of Internal Medicine III, University of Heidelberg, INF 410, 69120, Heidelberg, Germany, and.
Bers DM; the Department of Pharmacology, University of California, Davis, California 95616.
Thomas DD; From the Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis Minnesota 55455.
Cornea RL; From the Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis Minnesota 55455, corne002@umn.edu.

J Biol Chem ; 291(30): 15896-907, 2016 07 22.

Article em En | MEDLINE | ID: mdl-27226555

Assuntos

Cálcio/química; Calmodulina/química; Canal de Liberação de Cálcio do Receptor de Rianodina/química; Proteínas S100/química; Animais; Cálcio/metabolismo; Calmodulina/genética; Calmodulina/metabolismo; Transferência Ressonante de Energia de Fluorescência/métodos; Humanos; Músculo Esquelético/química; Músculo Esquelético/metabolismo; Miocárdio/química; Miocárdio/metabolismo; Ligação Proteica; Canal de Liberação de Cálcio do Receptor de Rianodina/metabolismo; Proteínas S100/genética; Proteínas S100/metabolismo; Suínos

Palavras-chave

FKBP12.6; calcium channel; calmodulin (CaM); fluorescence lifetime; fluorescence resonance energy transfer (FRET); sarcoplasmic reticulum (SR); structure-function

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Calmodulina / Proteínas S100 / Cálcio / Canal de Liberação de Cálcio do Receptor de Rianodina Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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