Accelerated high-bandwidth MR spectroscopic imaging using compressed sensing.
Magn Reson Med
; 76(2): 369-79, 2016 08.
Article
em En
| MEDLINE
| ID: mdl-27228088
ABSTRACT
PURPOSE:
To develop a compressed sensing (CS) acceleration method with a high spectral bandwidth exploiting the spatial-spectral sparsity of MR spectroscopic imaging (MRSI).METHODS:
Accelerations were achieved using blip gradients during the readout to perform nonoverlapped and stochastically delayed random walks in kx -ky -t space, combined with block-Hankel matrix completion for efficient reconstruction. Both retrospective and prospective CS accelerations were applied to (13) C MRSI experiments, including in vivo rodent brain and liver studies with administrations of hyperpolarized [1-(13) C] pyruvate at 7.0 Tesla (T) and [2-(13) C] dihydroxyacetone at 3.0 T, respectively.RESULTS:
In retrospective undersampling experiments using in vivo 7.0 T data, the proposed method preserved spectral, spatial, and dynamic fidelities with R(2) ≥ 0.96 and ≥ 0.87 for pyruvate and lactate signals, respectively, 750-Hz spectral separation, and up to 6.6-fold accelerations. In prospective in vivo experiments, with 3.8-fold acceleration, the proposed method exhibited excellent spatial localization of metabolites and peak recovery for pyruvate and lactate at 7.0 T as well as for dihydroxyacetone and its metabolic products with a 4.5-kHz spectral span (140 ppm at 3.0 T).CONCLUSIONS:
This study demonstrated the feasibility of a new CS approach to accelerate high spectral bandwidth MRSI experiments. Magn Reson Med 76369-379, 2016. © 2016 Wiley Periodicals, Inc.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Algoritmos
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Química Encefálica
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Imageamento por Ressonância Magnética
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Compressão de Dados
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Imagem Molecular
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Espectroscopia de Ressonância Magnética Nuclear de Carbono-13
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Fígado
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article