Surveillance of Immunosuppression During Pregnancy After Heart Transplantation: Case Report.
Transplant Proc
; 48(3): 978-81, 2016 Apr.
Article
em En
| MEDLINE
| ID: mdl-27234783
ABSTRACT
BACKGROUND:
Transplantation and immunosuppressive drugs are major limitations to the success of pregnancy. In 1988, the first pregnancy after a heart transplant was reported, which has given female recipients the hope to give birth. During pregnancy, physiologic changes with increased blood volume and hemodilution may influence blood drug level. CASE REPORT We reported our experience in monitoring on immunosuppressive drugs for 2 cases. Both of them underwent heart transplantation in 2006 and were 34 and 37 years old at time of pregnancy. For both cases, we frequently monitored the blood level and increased the dosage of immunosuppressive drugs accordingly. Both cases had uneventful pregnancy and delivery to healthy babies at the National Taiwan University Hospital in Taiwan. Their postpartum courses were uneventful as well.CONCLUSIONS:
We advocate adjusting the immunosuppressive dosage according to the blood level before pregnancy.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Complicações Cardiovasculares na Gravidez
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Transplante de Coração
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Terapia de Imunossupressão
/
Rejeição de Enxerto
Tipo de estudo:
Screening_studies
Limite:
Adult
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Female
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Humans
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Newborn
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Pregnancy
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article