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Brain structure, executive function and appetitive traits in adolescent obesity.
de Groot, C J; van den Akker, E L T; Rings, E H H M; Delemarre-van de Waal, H A; van der Grond, J.
Afiliação
  • de Groot CJ; Willem-Alexander Children's Hospital, Leiden University Medical Center, Leiden, The Netherlands.
  • van den Akker ELT; Sophia Children's Hospital, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Rings EHHM; Willem-Alexander Children's Hospital, Leiden University Medical Center, Leiden, The Netherlands.
  • Delemarre-van de Waal HA; Sophia Children's Hospital, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • van der Grond J; Willem-Alexander Children's Hospital, Leiden University Medical Center, Leiden, The Netherlands.
Pediatr Obes ; 12(4): e33-e36, 2017 08.
Article em En | MEDLINE | ID: mdl-27241878
BACKGROUND: Children with obesity show differences in brain structure, executive function and appetitive traits when compared with lean peers. Little is known on the relationship between brain structure and these traits. OBJECTIVES: To investigate the relationship between differences in brain structure and executive function and appetitive traits, in obese and lean adolescents. METHODS: MRI was used to measure cortical thickness and subcortical volumes. Executive function was measured by a Stop Signal-and a Choice Delay Task. Appetitive traits were measured using the Child Eating Behaviour Questionnaire. RESULTS: Adolescents with obesity had greater volumes of the pallidum; 1.78 mL (SE 0.03, p=0.014), when compared with controls; 1.65 mL (SE 0.02). In the group with obesity, greater pallidum volume was positively associated with the ability to delay reward in the Choice Delay Task (p=0.012). CONCLUSION: The association between pallidum volumes and Choice Delay Task in obese adolescents supports the hypothesis that the pallidum plays an important role in executive dysfunction in obese children.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Comportamento Alimentar / Função Executiva / Obesidade Infantil Limite: Adolescent / Child / Female / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Comportamento Alimentar / Função Executiva / Obesidade Infantil Limite: Adolescent / Child / Female / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article