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A Pharmacokinetic Modeling Approach to Predict the Contribution of Active Metabolites to Human Efficacious Dose.
Martin, Iain J; Hill, Susan E; Baker, James A; Deshmukh, Sujal V; Mulrooney, Erin F.
Afiliação
  • Martin IJ; Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Merck Research Laboratories, Boston, Massachusetts iain.martin@merck.com.
  • Hill SE; Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Merck Research Laboratories, Boston, Massachusetts.
  • Baker JA; Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Merck Research Laboratories, Boston, Massachusetts.
  • Deshmukh SV; Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Merck Research Laboratories, Boston, Massachusetts.
  • Mulrooney EF; Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Merck Research Laboratories, Boston, Massachusetts.
Drug Metab Dispos ; 44(8): 1435-40, 2016 08.
Article em En | MEDLINE | ID: mdl-27260151
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cálculos da Dosagem de Medicamento / Descoberta de Drogas / Modelos Biológicos / Antineoplásicos Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cálculos da Dosagem de Medicamento / Descoberta de Drogas / Modelos Biológicos / Antineoplásicos Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article