Quantitative proteomics reveals that distant recurrence-associated protein R-Ras and Transgelin predict post-surgical survival in patients with Stage III colorectal cancer.

Xu, Lai; Gao, Yanpan; Chen, Yanyu; Xiao, Yi; He, Qingzhong; Qiu, Huizhong; Ge, Wei

Xu, Lai; Gao, Yanpan; Chen, Yanyu; Xiao, Yi; He, Qingzhong; Qiu, Huizhong; Ge, Wei.

Afiliação

Xu L; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
Gao Y; National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, 100005, China.
Chen Y; National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, 100005, China.
Xiao Y; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
He Q; National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, 100005, China.
Qiu H; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
Ge W; National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, 100005, China.

Oncotarget ; 7(28): 43868-43893, 2016 Jul 12.

Article em En | MEDLINE | ID: mdl-27270312

Assuntos

Biomarcadores Tumorais/análise; Neoplasias Colorretais/patologia; Proteínas dos Microfilamentos/biossíntese; Proteínas Musculares/biossíntese; Recidiva Local de Neoplasia/patologia; Proteínas ras/biossíntese; Adulto; Idoso; Neoplasias Colorretais/metabolismo; Neoplasias Colorretais/mortalidade; Intervalo Livre de Doença; Feminino; Humanos; Estimativa de Kaplan-Meier; Masculino; Proteínas dos Microfilamentos/análise; Pessoa de Meia-Idade; Proteínas Musculares/análise; Recidiva Local de Neoplasia/metabolismo; Recidiva Local de Neoplasia/mortalidade; Prognóstico; Modelos de Riscos Proporcionais; Proteômica/métodos; Proteínas ras/análise

Palavras-chave

R-Ras and Transgelin; Stage III colorectal cancer; post-surgical recurrence; prognostic biomarker; quantitative proteomics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Biomarcadores Tumorais / Proteínas ras / Proteínas dos Microfilamentos / Proteínas Musculares / Recidiva Local de Neoplasia Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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