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Model-based exposure-response analysis to quantify age related differences in the response to scopolamine in healthy subjects.
Alvarez-Jimenez, Ricardo; Groeneveld, Geert Jan; van Gerven, Joop M A; Goulooze, Sebastiaan C; Baakman, Anne Catrien; Hay, Justin L; Stevens, Jasper.
Afiliação
  • Alvarez-Jimenez R; Centre for Human Drug Research, 2333, CL, Leiden, the Netherlands. ralvarez@chdr.nl.
  • Groeneveld GJ; Centre for Human Drug Research, 2333, CL, Leiden, the Netherlands.
  • van Gerven JM; Neurology Department, VU University Medical Center, 1081, HV, Amsterdam, the Netherlands.
  • Goulooze SC; Centre for Human Drug Research, 2333, CL, Leiden, the Netherlands.
  • Baakman AC; Neurology Department, Leiden University Medical Center, 2333, ZA, Leiden, the Netherlands.
  • Hay JL; Centre for Human Drug Research, 2333, CL, Leiden, the Netherlands.
  • Stevens J; Leiden Academic Center for Drug Research, Division of Pharmacology, Faculty of Mathematics and Natural Sciences, Leiden University, 2333, CC, Leiden, the Netherlands.
Br J Clin Pharmacol ; 82(4): 1011-21, 2016 10.
Article em En | MEDLINE | ID: mdl-27273555

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Escopolamina / Envelhecimento / Cognição Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Escopolamina / Envelhecimento / Cognição Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article