RNA Exosome Complex Regulates Stability of the Hepatitis B Virus X-mRNA Transcript in a Non-stop-mediated (NSD) RNA Quality Control Mechanism.

Aly, Hussein H; Suzuki, Junya; Watashi, Koichi; Chayama, Kazuaki; Hoshino, Shin-Ichi; Hijikata, Makoto; Kato, Takanobu; Wakita, Takaji

Aly, Hussein H; Suzuki, Junya; Watashi, Koichi; Chayama, Kazuaki; Hoshino, Shin-Ichi; Hijikata, Makoto; Kato, Takanobu; Wakita, Takaji.

Afiliação

Aly HH; From the Department of Virology II, National Institute of Infectious Diseases, Tokyo 162-8640, Japan, ahussein@nih.go.jp.
Suzuki J; From the Department of Virology II, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
Watashi K; From the Department of Virology II, National Institute of Infectious Diseases, Tokyo 162-8640, Japan, Department of Applied Biological Science, Tokyo University of Science, Noda 278-8510, Japan, Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST),
Chayama K; Department of Gastroenterology and Metabolism, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8551, Japan.
Hoshino S; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan, and.
Hijikata M; Laboratory of Human Tumor Viruses, Institute for Virus Research, Kyoto University, Kyoto 606-8507, Japan.
Kato T; From the Department of Virology II, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
Wakita T; From the Department of Virology II, National Institute of Infectious Diseases, Tokyo 162-8640, Japan, wakita@nih.go.jp.

J Biol Chem ; 291(31): 15958-74, 2016 07 29.

Article em En | MEDLINE | ID: mdl-27281821

Assuntos

Complexo Multienzimático de Ribonucleases do Exossomo/metabolismo; Vírus da Hepatite B/metabolismo; Estabilidade de RNA; RNA Mensageiro/metabolismo; RNA Viral/metabolismo; Transativadores/biossíntese; Códon de Iniciação/genética; Códon de Iniciação/metabolismo; DNA Helicases/genética; DNA Helicases/metabolismo; Complexo Multienzimático de Ribonucleases do Exossomo/genética; Células Hep G2; Vírus da Hepatite B/genética; Humanos; RNA Mensageiro/genética; RNA Viral/genética; Transativadores/genética; Proteínas Virais Reguladoras e Acessórias

Palavras-chave

HBS1L; Non-Stop mediated RNA Decay (NSD); RNA Exosome; RNA degradation; RNA helicase; RNA-binding protein; SKIV2L; exosome complex; hepatitis B virus (HBV, Hep B); virus restriction factor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Mensageiro / RNA Viral / Transativadores / Vírus da Hepatite B / Estabilidade de RNA / Complexo Multienzimático de Ribonucleases do Exossomo Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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